Doxorubicin loaded Polymeric Nanoparticulate Delivery System to overcome drug...
Background: Drug resistance is a primary hindrance for the efficiency of chemotherapy against osteosarcoma. Although chemotherapy has improved the prognosis of osteosarcoma patients dramatically after...
View ArticleInhibition of ABCB1 (MDR1) expression by an siRNA nanoparticulate delivery...
Background: The use of neo-adjuvant chemotherapy in treating osteosarcoma has improved patients’ average 5 year survival rate from 20% to 70% in the past 30 years. However, for patients who progress...
View ArticleMulti-functional nanocarriers to overcome tumor drug resistance
The development of resistance to variety of chemotherapeutic agents is one of the major challenges in effective cancer treatment. Tumor cells are able to generate a multi-drug resistance (MDR)...
View ArticleRole of hypoxia and glycolysis in the development of multi-drug resistance in...
Background The development of multi-drug resistant (MDR) cancer is a significant challenge in the clinical treatment of recurrent disease. Hypoxia is an environmental selection pressure that...
View ArticleNon-viral eNOS gene delivery and transfection with stents for the treatment...
Background In this study, we have examined local non-viral gene delivery, transfection, and therapeutic efficacy of endothelial nitric oxide synthase (eNOS) encoding plasmid DNA administered using...
View ArticleTherapeutic efficacy and safety of paclitaxel/lonidamine loaded EGFR-targeted...
The treatment of multi-drug resistant (MDR) cancer is a clinical challenge. Many MDR cells over-express epidermal growth factor receptor (EGFR). We exploit this expression through the development of...
View ArticleDoxorubicin loaded polymeric nanoparticulate delivery system to overcome drug...
Background: Drug resistance is a primary hindrance for the efficiency of chemotherapy against osteosarcoma. Although chemotherapy has improved the prognosis of osteosarcoma patients dramatically after...
View ArticleNon-viral eNOS gene delivery and transfection with stents for the treatment...
Background In this study, we have examined local non-viral gene delivery, transfection, and therapeutic efficacy of endothelial nitric oxide synthase (eNOS) encoding plasmid DNA administered using...
View ArticleInhibition of ABCB1 (MDR1) expression by an siRNA nanoparticulate delivery...
Background: The use of neo-adjuvant chemotherapy in treating osteosarcoma has improved patients’ average 5 year survival rate from 20% to 70% in the past 30 years. However, for patients who progress...
View ArticleMulti-functional nanocarriers to overcome tumor drug resistance
The development of resistance to variety of chemotherapeutic agents is one of the major challenges in effective cancer treatment. Tumor cells are able to generate a multi-drug resistance (MDR)...
View ArticleTherapeutic efficacy and safety of paclitaxel/lonidamine loaded EGFR-targeted...
The treatment of multi-drug resistant (MDR) cancer is a clinical challenge. Many MDR cells over-express epidermal growth factor receptor (EGFR). We exploit this expression through the development of...
View ArticleRole of hypoxia and glycolysis in the development of multi-drug resistance in...
Background The development of multi-drug resistant (MDR) cancer is a significant challenge in the clinical treatment of recurrent disease. Hypoxia is an environmental selection pressure that...
View ArticleRole of hypoxia and glycolysis in the development of multi-drug resistance in...
Background The development of multi-drug resistant (MDR) cancer is a significant challenge in the clinical treatment of recurrent disease. Hypoxia is an environmental selection pressure that...
View ArticleTherapeutic efficacy and safety of paclitaxel/lonidamine loaded EGFR-targeted...
The treatment of multi-drug resistant (MDR) cancer is a clinical challenge. Many MDR cells over-express epidermal growth factor receptor (EGFR). We exploit this expression through the development of...
View ArticleMulti-functional nanocarriers to overcome tumor drug resistance
The development of resistance to variety of chemotherapeutic agents is one of the major challenges in effective cancer treatment. Tumor cells are able to generate a multi-drug resistance (MDR)...
View ArticleInhibition of ABCB1 (MDR1) expression by an siRNA nanoparticulate delivery...
Background: The use of neo-adjuvant chemotherapy in treating osteosarcoma has improved patients’ average 5 year survival rate from 20% to 70% in the past 30 years. However, for patients who progress...
View ArticleNon-viral eNOS gene delivery and transfection with stents for the treatment...
Background In this study, we have examined local non-viral gene delivery, transfection, and therapeutic efficacy of endothelial nitric oxide synthase (eNOS) encoding plasmid DNA administered using...
View ArticleDoxorubicin loaded polymeric nanoparticulate delivery system to overcome drug...
Background: Drug resistance is a primary hindrance for the efficiency of chemotherapy against osteosarcoma. Although chemotherapy has improved the prognosis of osteosarcoma patients dramatically after...
View Article